The two volume set LNCS 16574 and 16575 constitutes the proceedings of the International Work-Conference on the Interplay Between Natural and Artificial Computation, IWINAC 2026, held in Canary Islands, Spain, during May 26–29, 2026.

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The 93 full papers included in this book were carefully reviewed and selected from 187 submissions. They were organized in topical sections as follows:

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Part I: Machine Learning in Neuroscience; Functional Evaluation of Neuromotor and Cognitive Disorders; Intelligent Systems for the Study and Support of Youth Mental Health; Socio-Cognitive, Affective and Physiological Computing; Intelligent Systems for Assessment, Treatment, and Assistance in early stages of Alzheimer; Neuroprosthesis, Ethics; and European Culture and Technology Lab;

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Part II: Machine Learning in Computer Vision and Robotics; Robotics; Bio-Inspired Computing Approaches; Social and Civil Engineering through Human AI Translations; Explainable, Robust and Trustworthy Machine Learning and its Applications; Learning tools to lecture; and Other Applications.

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Artificial Intelligence for Neuroscience, Mental Health, and Neurodegenerative Disorders

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