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Tony K.L.
Clinical Pharmacokinetic and Pharmacodynamic Drug Interactions Associated with Antimalarials
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2818346Clinical Pharmacokinetic and Pharmacodynamic Drug Interactions Associated with Antimalarialshttps://www.gandhi.com.mx/clinical-pharmacokinetic-and-pharmacodynamic-drug-interactions-associated-with-antimalarials-9783319105277/phttps://gandhi.vtexassets.com/arquivos/ids/2826463/6d92ae1e-ccbd-4c5b-b667-21133338e328.jpg?v=6383845045251300009621069MXNSpringer International PublishingInStock/Ebooks/<p>This comprehensive review provides a systematic, unbiased analysis, critique and summary of the available literature and generates novel clinical decision-making algorithms which can aid clinicians and scientists in practice management and research development. Potential mechanisms for the identified drug interactions are deduced from available preclinical and in vitro data which are interpreted in the context of the in vivo findings. Current limitations and gaps in the literature are summarized, and potential future research directions / experimentations are also suggested. In addition to the main objective to review the available clinical pharmacokinetic and pharmacodynamic drug interactions associated with WHO-recommended antimalarial drugs on the market today (i.e. chloroquine, amodiaquine, sulfadoxine, pyrimethamine, mefloquine, artemisinin, artemether, artesunate, dihydroartemisinin, artemotil, lumefantrine, primaquine, atovaquone, proguanil, piperaquine and quinine), this book also provides succinct chapter summaries on the epidemiology of malaria infection, diagnosis and therapeutics, in vivo pharmacology and chemistry, preclinical pharmacology, in vitro pharmacodynamics, in vitro reaction phenotyping, and in vitro drug-drug interaction data associated with the identified antimalarial drugs.</p>...2754504Clinical Pharmacokinetic and Pharmacodynamic Drug Interactions Associated with Antimalarials9621069https://www.gandhi.com.mx/clinical-pharmacokinetic-and-pharmacodynamic-drug-interactions-associated-with-antimalarials-9783319105277/phttps://gandhi.vtexassets.com/arquivos/ids/2826463/6d92ae1e-ccbd-4c5b-b667-21133338e328.jpg?v=638384504525130000InStockMXN99999DIEbook20149783319105277_W3siaWQiOiIyYTA2NzMyZC1hNGQ0LTQ3OWItOTI0Mi1kODA5ZmYxZDFhN2MiLCJsaXN0UHJpY2UiOjEwMzcsImRpc2NvdW50IjoxMDMsInNlbGxpbmdQcmljZSI6OTM0LCJpbmNsdWRlc1RheCI6dHJ1ZSwicHJpY2VUeXBlIjoiV2hvbGVzYWxlIiwiY3VycmVuY3kiOiJNWE4iLCJmcm9tIjoiMjAyNC0xMS0xMFQxNTowMDowMFoiLCJ0byI6IjIwMjQtMTEtMzBUMjM6NTk6NTlaIiwicmVnaW9uIjoiTVgiLCJpc1ByZW9yZGVyIjpmYWxzZX0seyJpZCI6ImM3ZmZjMjVmLTA4NzQtNDc5Yi1iYTdlLWE1NzljZjhjOGIyYSIsImxpc3RQcmljZSI6MTA3OSwiZGlzY291bnQiOjEwOCwic2VsbGluZ1ByaWNlIjo5NzEsImluY2x1ZGVzVGF4Ijp0cnVlLCJwcmljZVR5cGUiOiJXaG9sZXNhbGUiLCJjdXJyZW5jeSI6Ik1YTiIsImZyb20iOiIyMDI0LTEyLTAxVDAwOjAwOjAwWiIsInJlZ2lvbiI6Ik1YIiwiaXNQcmVvcmRlciI6ZmFsc2V9XQ==9783319105277_<p>This comprehensive review provides a systematic, unbiased analysis, critique and summary of the available literature and generates novel clinical decision-making algorithms which can aid clinicians and scientists in practice management and research development. Potential mechanisms for the identified drug interactions are deduced from available preclinical and in vitro data which are interpreted in the context of the in vivo findings. Current limitations and gaps in the literature are summarized, and potential future research directions / experimentations are also suggested. In addition to the main objective to review the available clinical pharmacokinetic and pharmacodynamic drug interactions associated with WHO-recommended antimalarial drugs on the market today (i.e. chloroquine, amodiaquine, sulfadoxine, pyrimethamine, mefloquine, artemisinin, artemether, artesunate, dihydroartemisinin, artemotil, lumefantrine, primaquine, atovaquone, proguanil, piperaquine and quinine), this book also provides succinct chapter summaries on the epidemiology of malaria infection, diagnosis and therapeutics, in vivo pharmacology and chemistry, preclinical pharmacology, in vitro pharmacodynamics, in vitro reaction phenotyping, and in vitro drug-drug interaction data associated with the identified antimalarial drugs.</p>(*_*)9783319105277_<p>This comprehensive review provides a systematic, unbiased analysis, critique and summary of the available literature and generates novel clinical decision-making algorithms which can aid clinicians and scientists in practice management and research development. Potential mechanisms for the identified drug interactions are deduced from available preclinical and in vitro data which are interpreted in the context of the in vivo findings. Current limitations and gaps in the literature are summarized, and potential future research directions / experimentations are also suggested. In addition to the main objective to review the available clinical pharmacokinetic and pharmacodynamic drug interactions associated with WHO-recommended antimalarial drugs on the market today (i.e. chloroquine, amodiaquine, sulfadoxine, pyrimethamine, mefloquine, artemisinin, artemether, artesunate, dihydroartemisinin, artemotil, lumefantrine, primaquine, atovaquone, proguanil, piperaquine and quinine), this book also provides succinct chapter summaries on the epidemiology of malaria infection, diagnosis and therapeutics, in vivo pharmacology and chemistry, preclinical pharmacology, in vitro pharmacodynamics, in vitro reaction phenotyping, and in vitro drug-drug interaction data associated with the identified antimalarial drugs.</p>...9783319105277_Springer International Publishinglibro_electonico_9058da4a-97eb-33b1-8449-6eda3abbe71c_9783319105277;9783319105277_9783319105277Tony K.L.InglésMéxico2014-11-10T00:00:00+00:00Springer International Publishing