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Michel Roger
Neocortical Grafting to Newborn and Adult Rats: Developmental, Anatomical and Functional Aspects
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3506028Neocortical Grafting to Newborn and Adult Rats: Developmental, Anatomical and Functional Aspectshttps://www.gandhi.com.mx/neocortical-grafting-to-newborn-and-adult-rats-developmental-anatomical-and-functional-aspects-9783642721793/phttps://gandhi.vtexassets.com/arquivos/ids/3200980/9d3689d8-3156-43e0-9789-5a21e6971e8c.jpg?v=63838502083123000017561951MXNSpringer Berlin HeidelbergInStock/Ebooks/<p>The first experiments with neural transplantation into the brain (for a review, see Bjorklund and Stenevi 1985) were reported at the end of the last century by Thompson (1890), who took cortical tissue from adult cats and implanted the tissue pieces into the neocortex of adult dogs. The neurons did not survive, but the transplanted mass did not disintegrate entirely. Successful graft ing into the brain was reported later by Ranson (1909), who implanted spinal ganglia into the cerebral cortex of developing rats, and by Dunn (1917), who reported survival of implanted neonatal cortex into the cortex of newborn recipients. Another important step was made by Le Gros Clark (1940) who reported that, in the rabbit, embryonic (E) cortical tissue could be successfully grafted into the cortex of young recipients. Ex periments by Wallace and Das (1982), and Bjorklund and Stenevi (1984), showing behavioral effects of grafts, subsequently stimu lated a growing interest in neurotransplantation research. Intrac erebral grafting is now considered a powerful tool for addressing fundamental questions about development, regenerative, or re storative phenomena in the central nervous system (CNS) and is a potential therapy for neurodegenerative diseases.</p>...3442322Neocortical Grafting to Newborn and Adult Rats: Developmental, Anatomical and Functional Aspects17561951https://www.gandhi.com.mx/neocortical-grafting-to-newborn-and-adult-rats-developmental-anatomical-and-functional-aspects-9783642721793/phttps://gandhi.vtexassets.com/arquivos/ids/3200980/9d3689d8-3156-43e0-9789-5a21e6971e8c.jpg?v=638385020831230000InStockMXN99999DIEbook20139783642721793_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_<p>The first experiments with neural transplantation into the brain (for a review, see Bjorklund and Stenevi 1985) were reported at the end of the last century by Thompson (1890), who took cortical tissue from adult cats and implanted the tissue pieces into the neocortex of adult dogs. The neurons did not survive, but the transplanted mass did not disintegrate entirely. Successful graft ing into the brain was reported later by Ranson (1909), who implanted spinal ganglia into the cerebral cortex of developing rats, and by Dunn (1917), who reported survival of implanted neonatal cortex into the cortex of newborn recipients. Another important step was made by Le Gros Clark (1940) who reported that, in the rabbit, embryonic (E) cortical tissue could be successfully grafted into the cortex of young recipients. Ex periments by Wallace and Das (1982), and Bjorklund and Stenevi (1984), showing behavioral effects of grafts, subsequently stimu lated a growing interest in neurotransplantation research. Intrac erebral grafting is now considered a powerful tool for addressing fundamental questions about development, regenerative, or re storative phenomena in the central nervous system (CNS) and is a potential therapy for neurodegenerative diseases.</p>(*_*)9783642721793_<p>The first experiments with neural transplantation into the brain (for a review, see Bjorklund and Stenevi 1985) were reported at the end of the last century by Thompson (1890), who took cortical tissue from adult cats and implanted the tissue pieces into the neocortex of adult dogs. The neurons did not survive, but the transplanted mass did not disintegrate entirely. Successful graft ing into the brain was reported later by Ranson (1909), who implanted spinal ganglia into the cerebral cortex of developing rats, and by Dunn (1917), who reported survival of implanted neonatal cortex into the cortex of newborn recipients. Another important step was made by Le Gros Clark (1940) who reported that, in the rabbit, embryonic (E) cortical tissue could be successfully grafted into the cortex of young recipients. Ex periments by Wallace and Das (1982), and Bjorklund and Stenevi (1984), showing behavioral effects of grafts, subsequently stimu lated a growing interest in neurotransplantation research. Intrac erebral grafting is now considered a powerful tool for addressing fundamental questions about development, regenerative, or re storative phenomena in the central nervous system (CNS) and is a potential therapy for neurodegenerative diseases.</p>...9783642721793_Springer Berlin Heidelberglibro_electonico_72af2db0-c39e-3d35-b79c-55c5e6141c5a_9783642721793;9783642721793_9783642721793Michel RogerInglésMéxico2013-03-12T00:00:00+00:00Springer Berlin Heidelberg