9781771700535_

This book is based on an in-depth conversation between Howard Burton and Stephen Scherer, the GlaxoSmithKline Research Chair in Genome Sciences at the Hospital for Sick Children and University of Toronto. Stephen Scherer discusses his lifelong passion for science that culminated in his groundbreaking discovery of copy-number variation. This conversation also covers his exciting work in autism research and how copy number variation brings us a deeper understanding of both human variability and disease.

This carefully-edited book includes an introduction, More Things in DNA, Horatio..., and questions for discussion at the end of each chapter:

James Watson’s Legacy - From The Double Helix to NRC to chromosome 7
In the Lab - The first hints of copy number variation
Chromosome 7 - Mapping genetic markers to chromosomes
Back to Basics - Nucleotides, DNA, chromosomes, genes and mutations
Revolutionary Stirrings - Detecting copy number variation
Going Global - Large-scale variation for all
Variability and Evolution - Appreciating biological variability
Causes and Implications - Complexity galore: autism and other conditions
Towards Treatment - Early diagnoses and equilibrium-restoring medicines
The Definition of Diseases - More complicated that you might think
Probing Deeper - Stem cells, pleiotropy and environmental factors
Ethical and Societal Issues - Towards responsible progress
Future Possibilities - Potentially unravelling biological complexity
Contact with Autism - Serendipitous occurrences
Nobel Thoughts - The perks and perils of prizes
The Human Condition - Genetic windows on humanity

About Ideas Roadshow Conversations Series (100 books):

Presented in an accessible, conversational format, Ideas Roadshow books not only explore frontline academic research featuring world-leading researchers, including 3 Nobel Laureates, but also reveal the inspirations and personal journeys behind the research. Howard Burton holds a PhD in physics and an MA in philosophy, and was the Founding Director of Canada’s Perimeter Institute for Theoretical Physics.

(*_*)9781771700535_

This carefully-edited book includes an introduction, More Things in DNA, Horatio..., and questions for discussion at the end of each chapter:

James Watsons Legacy - From The Double Helix to NRC to chromosome 7
In the Lab - The first hints of copy number variation
Chromosome 7 - Mapping genetic markers to chromosomes
Back to Basics - Nucleotides, DNA, chromosomes, genes and mutations
Revolutionary Stirrings - Detecting copy number variation
Going Global - Large-scale variation for all
Variability and Evolution - Appreciating biological variability
Causes and Implications - Complexity galore: autism and other conditions
Towards Treatment - Early diagnoses and equilibrium-restoring medicines
The Definition of Diseases - More complicated that you might think
Probing Deeper - Stem cells, pleiotropy and environmental factors
Ethical and Societal Issues - Towards responsible progress
Future Possibilities - Potentially unravelling biological complexity
Contact with Autism - Serendipitous occurrences
Nobel Thoughts - The perks and perils of prizes
The Human Condition - Genetic windows on humanity

About Ideas Roadshow Conversations Series (100 books):

...

Our Human Variability

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